Research

Abstract:

In this research, Phenol derivatives have been reacted with aryl halides using 5 mol% Cu(I) Complex [CuClPPh3]4 as catalyst supported on Amberlyst A21. The typical reaction has been performed between p-cresol and bromobenzene. This reaction is achieved in o-xylene as solvent

However, the catalyst complex does not dissolve in o-xylene rather it acts as heterogeneous catalyst.

Therefore, it is filtrated at the end of the reaction and reused several times. Accordingly, new compounds were prepared by reacting some of bromoaryl derivatives with some Phenol derivatives.

It is anticipated that the synthesized compounds have a structure NSAIDs-likes that may find their applications in the pharmaceutical industries

Name of journal in which the research was published: 

International Letters of Chemistry, Physics and Astronomy.

Publication Date:

2016.

Link: 

Synthesis and Structure of New Compounds NSAIDs-Like Using a Heterogeneous Recyclable Catalyst